CUSIP No.
05348P401
1
|
NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
(entities only)
Baker Bros. Advisors LP
13-4093645
|
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions) (a)
¨
(b)
¨
|
3
|
SEC
USE ONLY
|
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
|
NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
|
5
|
SOLE VOTING POWER
18,558,487
|
6
|
SHARED VOTING POWER
-0-
|
7
|
SOLE DISPOSITIVE POWER
18,558,487
|
8
|
SHARED DISPOSITIVE POWER
-0-
|
9
|
AGGREGATE AMOUNT BENEFICIALLY OWNED BY
EACH REPORTING PERSON
18,558,487
|
10
|
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
¨
(See Instructions)
|
|
|
11
|
PERCENT OF CLASS REPRESENTED BY AMOUNT
IN ROW 9
10.8% (1)
|
12
|
TYPE OF REPORTING PERSON (See Instructions)
IA, PN
|
|
(1)
|
Based on 171,087,065 shares of common stock outstanding as of June 5, 2014, based upon information obtained from the Issuer
on June 5, 2014.
|
CUSIP No.
05348P401
1
|
NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
(entities only)
Baker Bros. Advisors (GP) LLC
46-3147749
|
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions) (a)
¨
(b)
¨
|
3
|
SEC
USE ONLY
|
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
|
NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
|
5
|
SOLE VOTING POWER
18,558,487
|
6
|
SHARED VOTING POWER
-0-
|
7
|
SOLE DISPOSITIVE POWER
18,558,487
|
8
|
SHARED DISPOSITIVE POWER
-0-
|
9
|
AGGREGATE AMOUNT BENEFICIALLY OWNED BY
EACH REPORTING PERSON
18,558,487
|
10
|
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
¨
(See Instructions)
|
|
|
|
11
|
PERCENT OF CLASS REPRESENTED BY AMOUNT
IN ROW 9
10.8% (1)
|
12
|
TYPE OF REPORTING PERSON (See Instructions)
HC, OO
|
|
(1)
|
Based on 171,087,065 shares of common stock outstanding as of June 5, 2014, based upon information obtained
from the Issuer on June 5, 2014.
|
CUSIP No.
05348P401
1
|
NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
(entities only)
Felix J. Baker
|
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions) (a)
¨
(b)
¨
|
3
|
SEC
USE ONLY
|
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
United States
|
NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
|
5
|
SOLE VOTING POWER
18,558,487
|
6
|
SHARED VOTING POWER
-0-
|
7
|
SOLE DISPOSITIVE POWER
18,558,487
|
8
|
SHARED DISPOSITIVE POWER
-0-
|
9
|
AGGREGATE AMOUNT BENEFICIALLY OWNED BY
EACH REPORTING PERSON
18,558,487
|
10
|
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
¨
(See Instructions)
|
|
|
11
|
PERCENT OF CLASS REPRESENTED BY AMOUNT
IN ROW 9
10.8% (1)
|
12
|
TYPE OF REPORTING PERSON (See Instructions)
IN, HC
|
|
(1)
|
Based on 171,087,065 shares of common stock outstanding
as of June 5, 2014, based upon information obtained from the Issuer on June 5, 2014.
|
CUSIP No.
05348P401
1
|
NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
(entities only)
Julian C. Baker
|
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions) (a)
¨
(b)
¨
|
3
|
SEC
USE ONLY
|
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
United States
|
NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
|
5
|
SOLE VOTING POWER
18,558,487
|
6
|
SHARED VOTING POWER
-0-
|
7
|
SOLE DISPOSITIVE POWER
18,558,487
|
8
|
SHARED DISPOSITIVE POWER
-0-
|
9
|
AGGREGATE AMOUNT BENEFICIALLY OWNED BY
EACH REPORTING PERSON
18,558,487
|
10
|
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
¨
(See Instructions)
|
|
|
11
|
PERCENT OF CLASS REPRESENTED BY AMOUNT
IN ROW 9
10.8% (1)
|
12
|
TYPE OF REPORTING PERSON (See Instructions)
IN, HC
|
|
(1)
|
Based on 171,087,065 shares of common stock outstanding as of June 5, 2014, based upon information obtained
from the Issuer on June 5, 2014.
|
|
Item 1(a)
|
Name of Issuer:
|
Avanir Pharmaceuticals,
Inc. (the “Issuer”)
|
Item 1(b)
|
Address of Issuer’s Principal Executive Offices:
|
20 Enterprise, Suite 200
Aliso Viejo, California 92656
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Item 2(a)
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Name of Person Filing:
|
This Schedule 13G is being filed jointly by the Baker Bros.
Advisors LP (the “Adviser”), Baker Bros. Advisors (GP) LLC (the “Adviser GP”), Felix J. Baker and Julian
C. Baker (collectively, the “Reporting Persons”).
|
Item 2(b)
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Address of Principal Business Office or, if None,
Residence:
|
The business address of each of
the Reporting Persons is:
c/o Baker Bros. Advisors LP
667 Madison Avenue, 21
st
Floor
New York, NY 10065
(212) 339-5690
The Adviser is a limited partnership organized under
the laws of the State of Delaware. The Adviser GP is a limited liability company organized under the laws of the State of Delaware.
The citizenship of each of Julian C. Baker and Felix J. Baker is the United States of America.
|
Item 2(d)
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Title of Class of Securities
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Common Stock, $0.0001
par value per share (“Common Stock”)
05348P401
|
Item 3.
|
If this statement is filed pursuant to §§240.13d-1(b)
or (c), check whether the person filing is a:
|
(a)
¨
Broker or dealer registered under Section 15 of the Exchange Act.
(b)
¨
Bank as defined in section 3(a)(6) of the Exchange Act.
(c)
¨
Insurance company as defined in section 3(a)(19) of the Exchange Act.
(d)
¨
Investment company registered under section 8 of the Investment Company Act of 1940.
(e)
x
An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E).
(f)
¨
An employee benefit plan or endowment fund in accordance with Rule 13d-1(b)(1)(ii)(F).
(g)
x
A parent holding company or control person in accordance with Rule 13d-1(b)(1)(ii)(G).
(h)
¨
A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act.
(i)
¨
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act
of 1940.
(j)
¨
Group, in accordance with Rule 13d-1(b)(1)(ii)(J).
Items 5 through 9 and 11 of each of the cover pages to this
Schedule 13G are incorporated herein reference. Certain securities of the Issuer are directly held by each of Baker Brothers Life
Sciences, L.P. (“Life Sciences”), 14159, L.P. (“14159”) and 667, L.P. (“667”, and together
with Life Sciences and 14159, the “Funds”). The information set forth below is based upon 171,087,065 shares of Common
Stock outstanding as of June 5, 2014 based upon information obtained from the Issuer on June 5, 2014. Such percentage figures are
calculated in accordance with Rule 13d-3 under the Securities Exchange Act of 1934, as amended.
|
|
Number of
|
|
|
Percent of
|
|
|
|
Shares of
|
|
|
Class
|
|
Name
|
|
Common Stock
|
|
|
Outstanding
|
|
|
|
|
|
|
|
|
667, L.P.
|
|
|
1,680,018
|
|
|
|
1.0
|
%
|
Baker Brothers Life Sciences, L.P.
|
|
|
16,469,825
|
|
|
|
9.6
|
%
|
14159, L.P.
|
|
|
408,644
|
|
|
|
0.2
|
%
|
Total
|
|
|
18,558,487
|
|
|
|
10.8
|
%
|
Pursuant to the amended and restated management agreements,
as amended, among the Adviser, the Funds and their respective general partners, the Funds’ respective general partners relinquished
to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds,
the Adviser has complete and unlimited discretion and authority with respect to the Funds’ investments and voting power over
investments.
The Adviser GP, Felix J. Baker and Julian C. Baker as principals
of the Adviser GP, and the Adviser may be deemed to be beneficial owners of securities of the Issuer directly held by the Funds,
and may be deemed to have the power to vote or direct the vote of and the power to dispose or direct the disposition of such securities.
The Reporting Persons disclaim beneficial ownership of the securities
held by each of the Funds, and this Schedule 13G shall not be deemed an admission that the Reporting Persons are the beneficial
owners of such securities for purposes of Section 13(d) or for any other purpose.
|
Item 5.
|
Ownership of Five Percent or Less of a Class.
|
If this statement
is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more
than five percent of the class of securities, check the following [ ]. N/A
|
Item 6.
|
Ownership of More than Five Percent on Behalf of
Another Person.
|
The information in Item 4 is incorporated
herein by reference.
|
Item 7.
|
Identification and Classification of the Subsidiary
Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
|
The information in Item 4 is incorporated
herein by reference.
By signing below I certify that, to the best of my knowledge
and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired
and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and
were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and
belief, I certify that the information set forth in this statement is true, complete and correct.
June 10, 2014
|
BAKER BROS. ADVISORS LP
By: Baker Bros. Advisors (GP) LLC, its general partner
|
|
|
|
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By:
|
/s/ Scott L. Lessing
|
|
|
Name: Scott L. Lessing
Title: President
|
|
BAKER BROS. ADVISORS (GP)
|
|
LLC
|
|
|
By:
|
/s/ Scott L. Lessing
|
|
|
Name: Scott L. Lessing
Title: President
|
|
/s/ Julian C. Baker
|
|
Julian C. Baker
|
|
|
|
/s/ Felix J. Baker
|
|
Felix J. Baker
|