ZymoGenetics Reports "Positive" Results In Melanoma Study

Date : 09/29/2010 @ 7:03AM
Source : Dow Jones News
Stock : Zymogenetics (MM) (ZGEN)
Quote : 9.76  0.0 (0.00%) @ 2:05AM

ZymoGenetics Reports "Positive" Results In Melanoma Study

Zymogenetics (MM) (NASDAQ:ZGEN)
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ZymoGenetics Inc. (ZGEN) said an experimental immunotherapy treatment for metastatic melanoma showed "positive survival" results in a mid-stage trial.

The data come in the midst of Bristol-Myers Squibb Co.'s (BMY) $836 million buyout of ZymoGenetics. Chief Executive Lamberto Andreotti has said the acquisition would strengthen its Hepatitis C portfolio.

In the study of 40 patients with advanced melanoma, participants were treated with one of three doses of the drug. The median overall survival rate was 12.4 months, with 53% surviving after a year. Overall response rate was 23% in evaluable patients, and progression-free survival was 4.3 months.

Common adverse effects were fatigue, rash, fever myalgia, anorexia, chills and nausea.

Among ZymoGenetics other products are Recothrom, a drug used in surgeries to prevent blood clotting, and six biologic drug candidates for atopic dermatitis.

ZymoGenetics shares closed Tuesday at $9.75--the buyout price--and were inactive premarket.

 
   -By Matt Jarzemsky, Dow Jones Newswires; 212-416-2240; matthew.jarzemsky@dowjones.com 
 
 
 

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